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Guotai Junan's annual strategy for innovative drugs in 2025: innovative pharmaceutical companies have accelerated into the harvest period, and the valuation has been at a historical low in the past five years. Guotai Junan said that the centralized purchasing policy has become stable, mature and normalized, and the marginal impact has weakened. Innovative drugs have gained policy inclination in the medical insurance negotiation. In the past two years, the policy has continued to promote pharmaceutical innovation, and the top-level design and local supporting chain support the development of innovative drugs. Commercial insurance is expected to bring new growth momentum to China's pharmaceutical market, and the overall industry trend is upward. At present, the trend of innovative drug industry is improving, the supply continues to accelerate, and a number of domestic innovative drugs are approved soon, which is expected to drive a new round of heavy volume. At the same time, the commercialization has achieved remarkable results and has occupied a dominant position in some sub-sectors. Pharma's performance continued to differentiate, and innovative drugs and just-needed drugs performed well. Biotech commercialization continues to increase, per capita yield continues to increase, the node of turning losses is approaching, and innovation ushers in the harvest period. Horizontal comparison: compared with overseas peers, the overall valuation of domestic innovative pharmaceutical companies is in a historically low range; Vertical comparison: the valuation of SW- pharmaceutical biology and SW- chemical preparations is at a historical low in the past five years, and it is expected that the valuation of subsequent sectors will pick up.The negotiation between Myriad and United Health Insurance may be extended to the beginning of 2025, and the negotiation between Myriad Genetics and UnitedHealthcare on the genetic test of Myriad may continue until the beginning of 2025. Myriad reiterated its estimate of the financial impact of the United Health Insurance Company's updated medical policy in 2024.Trump appointed TOM BARRACK as the US ambassador to Turkey.

Institution: In November, the average price of second-hand residential buildings in Baicheng dropped by 0.57% month-on-month. According to the 100-city price index of China's real estate index system, in November 2024, the average price of second-hand residential buildings in Baicheng fell by 0.57% month-on-month, narrowing by 0.03 percentage points from last month. It fell by 7.29% year-on-year. In November, the average price of second-hand residential buildings in the top ten cities fell by 0.17% month-on-month, which was 0.16 percentage points lower than that of the previous month. It fell by 7.16% year-on-year, and the decline was narrowed by 0.36 percentage points from the previous month. In terms of cities, the prices of second-hand houses in Shenzhen and Chengdu rose by 0.21% and 0.12% respectively. Nanjing had the largest decline from the previous month, with 0.60%; Wuhan, Hangzhou and Tianjin followed closely, with decreases of 0.43%, 0.42% and 0.31% respectively. Guangzhou, Shanghai and Beijing all experienced month-on-month declines of 0.1%-0.3%; Chongqing (the main city) has the smallest decline of 0.07%. In terms of year-on-year, Wuhan and Nanjing experienced large year-on-year declines, accounting for 10.82% and 10.24% respectively. Chongqing (the main city), Beijing, Hangzhou and Shanghai all experienced year-on-year declines of 7%-9%; The prices of second-hand houses in Tianjin, Guangzhou and Chengdu all fell by 5-7% year-on-year; Shenzhen fell by 4.42% year on year.Ministry of Finance of Korea: Korea's financial market is still facing uncertainty.Byte internal judges that the ceiling of AI dialogue products may not be high, so it is necessary to improve the priority of cutting and dreaming. It is learned from informed sources that Byte management judges that AI dialogue products (or chatbot products) may only be the "intermediate state" of AI products, and a more ideal product form for a long time requires a more visual user experience and a lower threshold for users to use. Therefore, Byte has promoted the product priority of Dreaming, and tried to create a "Tik Tok" in the AI ​ ​ era with a new path. In this regard, I asked the byte for verification, and the byte did not respond. (36Kr)

CITIC Jiantou: China's commercial space layout continues to land, and SpaceX's first mobile phone direct connection constellation has been built. CITIC Jiantou Research Report said that China's state-owned private enterprises have laid out one after another, and the satellite development and rocket launch modes have gradually transformed, and commercial space forces are expected to accelerate the layout process of low-orbit Internet. Recently, China Aerospace Science and Technology Corporation Commercial Satellite Co., Ltd. unveiled its design concept of Internet satellite for the first time, including standardization, low cost, integration, digitalization and scale. The company's production line in Tianjin has an annual production capacity of more than 100 satellites, and the satellite super factory in Wenchang, Hainan is expected to be put into operation in 2025, with an annual production capacity of 1,000 satellites. The third batch of networked satellites in Qian Fan (G60) constellation was successfully launched, and the number of satellites in orbit increased to 54. China Telecom invested 1 billion yuan to set up a new satellite company. Internationally, SpaceX has built the world's first low-orbit mobile phone direct connection constellation, and the three European aerospace giants Airbus Group, Terez Company and Leonardo Company want to jointly build a new satellite company.New Zealand appoints WINSTON PETERS as Minister of Railways.General Motors (GM): The unmanned business Cruise and GM Technical team will be merged, and the plan is expected to be completed in the first half of 2025. According to the priority of GM's capital allocation, GM will no longer fund Cruise's self-driving taxi development business.